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One challenge FDA face right now, when it comes to developing diagnostics that can help target the delivery of cancer drugs, is the way these diagnostics are sometimes labeled. When an in vitro diagnostic test gets approved, it’s often based on the results of studies with one specific drug. As a consequence, the labeling of the test often reflects the use of that diagnostic in conjunction with just one drug. And, in turn, the drug can reflect the use of that medicine in conjunction with just one diagnostic test. This sometimes narrow labeling that ties a drug to a specific diagnostic test happens even in cases where the diagnostic test is applicable to all drugs in a specific class of cancer medicines. This is a challenge given the way cancer care is emerging. Increasingly, new drugs are targeting specific molecular markers that drive the growth and spread of cancer. Sometimes, multiple drugs in a class of medicines target the same marker in a largely similar fashion. In these

Researchers have discovered that a hormone, fibroblast growth factor 21 (FGF21), is extremely elevated in mice with liver disease that mimics the same condition in patients with methylmalonic academia  (MMA), a serious genomic disorder. Based on this finding, medical teams treating patients with MMA will be able to measure FGF21 levels to predict how severely patients’ livers are affected and when to refer patients for liver transplants. The findings also might shed light on more common disorders such as fatty liver disease, obesity and diabetes by uncovering similarities in how MMA and these disorders affect energy metabolism and, more specifically, the function of mitochondria, the cells’ energy powerhouses. The study, conducted by researchers at the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health, was published Dec. 6 in JCI Insight. MMA is a genomic disease that impairs a person’s ability to break down food proteins and certain fatty

The National Institutes of Health announced  that enrollment for the Adolescent Brain Cognitive Development (ABCD) Study is now complete and, in early 2019, scientists will have access to baseline data from all ABCD Study participants. There are 11,874 youth, ages 9-10, participating in the study, including 2,100 young people who are twins or triplets. All will be followed through young adulthood.  The ABCD Study is a landmark study on brain development and child health that will increase understanding of environmental, social, genetic, and other biological factors that affect brain and cognitive development and can enhance or disrupt a young person’s life trajectory. Coordinated by the National Institute on Drug Abuse and the National Institute on Alcohol Abuse and Alcoholism, the study is supported by eight other NIH institutes and offices, as well as the Centers for Disease Control and Prevention and other federal partners. The study—being conducted at 21 research sites aroun

Indian Institute of Science Education and Research Pune is a premier autonomous Institution established by the Ministry of Human Resource Development, Government of India, for the promotion of high-quality science education and research in the country. Post :  Research Associate Name of the Project :  “Engineering and modification of bacterial toxins to combat chewing insect pests of Cotton” Project Code :  008 Minimum Educational Qualifications & Experience Ph.D. in any branch of Life Sciences. Candidate must have at least 1 year research experience after Ph.D. Candidate must have at least one first author peer reviewed international publication from his / her PhD Experience: 1. Expression cloning, recombinant expression, purification of recombinant enzymes 2. SDS-PAGE, Western Blotting, ELISA and protein activity assays Preference  :  Candidates having experience with HPLC and protein purification will be preferred Tenure of the appointment :  Initially for a period

The Centre for Cellular and Molecular Biology (CCMB) is one of the constituent national laboratories of the Council of Scientific & Industrial Research (CSIR) and a premier scientific institute that conducts high quality research in frontier and multi-disciplinary areas of modern biology. Research Associate - I No of posts :  03 Upper age limit  :  35 years. Fellowship :   Rs. 36,000/- p.m. to 40,000/- p.m. (depending on the experience) + HRA as applicable/admissible Essential qualification :  Ph.D. in Life Sciences/ Genetics and Plant Breeding/ Biotechnology/ Botany/ Biochemistry/Bioinformatics with research experience in crop plants (preferably rice) OR M. Tech. in Life Sciences/ Genetics and Plant Breeding/ Biotechnology/ Botany/ Biochemistry/Bioinformatics with 60% marks and 2 years of research experience in crop plants (preferably rice) Desirable qualification :  2 years of research experience, research publications in plant breeding, plant molecular biology/ pla

We are the manufacturer and exporter of pharmaceuticals from head office Rohini sector 9 Delhi and factories at Bahadurgarh and vadodara Post :  Pharmacist Job Description Pharmaceuticals Products development for Export / Qc/ Qa/ Mfg. No of Posts :  02 Qualification :  B.Pharma , M.Pharma , B.Sc , M.Sc freshers also apply Additional Information Experience :   fresher Qualification :   B.Pharma , M.Pharma , B.Sc , M.Sc Location :  Delhi Industry Type :  Pharma Functional Area :  Pharmaceuticals Salary :  Rs 20000 Send cv & Photo at  paksonspharma@gmail.com   Posted by Sushil Aggarwal Paksons Pharmaceuticals Pvt Ltd